Pharmaceutical Technology on MSN

RNA-targeting small molecules: A new frontier of drug discovery

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology ...

Tiny, 45 base long RNA can make copies of itself

These random molecules were fed a collection of three-base-long RNAs, each linked to a chemical tag. The idea was that if a molecule is capable of ligating one of these short RNA fragments to itself, ...