Trying to segregate disorganized chromosomes is a feat akin to unpacking tangled Christmas lights. But through largely unknown processes, proteins called condensins help organize DNA during cell ...

Tagmentation enables tunable and sensitive single-molecule real-time sequencing. Credit: Nature Genetics (2024). DOI: 10.1038/s41588-024-01748-0 In recent years, technologies that allow scientists to ...

The authors used a combination of super-resolution imaging techniques and liquid pressure flow to fine-tune the stretch ratio of a DNA molecule, improving the lateral resolution of side-by-side ...

Atomic Force Microscopy-based SMFS is widely used due to its high force sensitivity and spatial resolution. In this technique, a biomolecule is attached between a surface and an AFM cantilever. As the ...

Thought LeadersMaxim Molodtsov, Ph.D. Randhir Kumar, Ph.D. From optical trapping experiments to insights into molecular force generation, Dr. Maxim Molodtsov shared how his research is uncovering the ...

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily. So for ...

Researchers at the University of Missouri announced on March 1, 2026, that they are developing what they describe as a ...

Two new tools created at Gladstone Institutes allow scientists to study DNA at single-molecule resolution using fewer cells than previously required, with clear applications for cancer and many other ...

Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum ...