UConn Center on Aging researchers have published a new editorial in the journal Aging titled "Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?" In ...
The induction of polyploidy — that is, duplication or acquisition of entire sets of chromosomes — is a common event in the evolutionary histories of various species. The evolutionary consequences of ...
Confocal microscopy is performed with nuclear reporters and stains, nuclear segmentation with ilastik is conducted, and a machine learning method is used to classify the ploidy of each nucleus. Colors ...
Assistant Professor of Biology Vicki Losick admits she harbors a desire to change the world a little bit. “I want to make ‘polyploidy’ a household word,” Losick said in her Higgins Hall office, next ...
Scientists have developed a theoretical model that uncovers the dual role of polyploidy -- organisms carrying extra genome copies -- in evolution. Their findings reveal that polyploidy can stabilize ...
Polyploidy is a state where a cell contains more copies of the genetic material than the usual "diploid" cell, which contains two copies. Polyploidy often occurs in human diseases and cancers, and its ...
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Polyploidy-induced senescence may influence aging and cancer risk
A new editorial was published in Volume 18 of Aging-US on February 8, 2026, titled "Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?" In this ...
For decades, scientists have struggled to untangle the genetic complexity of crops with multiple chromosome sets. Now, researchers have unveiled a cost-effective sequencing method, dpMIG-seq, that ...
A Brazilian study published in Scientific Reports shows that artificial intelligence (AI) can be used to create efficient models for genomic selection of sugarcane and forage grass varieties and ...
Characterization of molecular response and progression in patients with metastatic HR+/HER2- breast cancer receiving endocrine therapy and CDK4/6 inhibitors using a high-sensitivity tumor-informed ...
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