Communication between oocytes and granulosa cells is essential for oocyte formation, dormancy, reawakening, and maturation. Researchers have demonstrated that a protein complex called the exocyst ...

DLGAP5 is proposed as a causal gene related to oocyte meiosis disorder for the first time. It expanded the current spectrum of pathogenic genes responsible for the phenotype of oocyte maturation and ...

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without ...

Y.A.R. White et al., “Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women,” Nat Med, 18:413–21, 2012. Every middle schooler learns that women are born ...

Tsukuba, Japan—In many mammals, a limited number of oocytes are responsible for producing the next generation. Oocytes grow within follicles, which consist of an oocyte and the surrounding granulosa ...