Cancer begins when mutations in specific genes override the body’s built-in controls on cell division, allowing rogue cells ...

When cancer cells begin to die within tumors, they expose signals on their surface that indicate they are dying. Macrophages then detect these signals and engage in phagocytosis, where they eat the ...

Boron agents termed GluBs, developed by Science Tokyo researchers, have overcome a key limitation in cancer therapy by entering tumor cells through a pathway that standard drugs cannot use. The GluBs ...

We are what we eat. While both the beneficial and detrimental effects of diet on health are well-documented, from boosting ...

UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block ...

Researchers designed CAR T cells that locally release VEGF-blocking molecules, weakening tumor defenses and boosting immune ...

A multidisciplinary team of researchers at Princeton University conducted a study to find out what patients diagnosed with ...

A new study shows cancer cells depend on vitamin B7 to use pyruvate as backup fuel, opening new strategies for targeted therapy.

TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...

A tumor is an abnormal mass of tissue that forms when cells grow and divide more than they should, or do not die when they should. Tumors may be benign ...