As a researcher, I still remember the discomfort I felt every time I had to sacrifice laboratory animals for an experiment.

Assembloids: A Versatile Platform for Human Tissue Modeling. This schematic illustrates the classification of assembloids based on four key assembly strategies—multi-region, multi-lineage, ...

Geroscience examines the underlying biology of aging to delay chronic diseases and extend the healthy years of human life.

A new, easily adopted, 3D-printed device will enable scientists to create models of human tissue with even greater control and complexity. An interdisciplinary group of researchers at the University ...

Before you ever set foot on a spacecraft bound for deep space, tiny replicas of your organs might make the journey first. Suspended in microgravity aboard a research mission, this organ-on-a-chip, or ...

As brain organoids replicate aspects of the brain's physiology, organoids hold the potential to reveal new insights about human tissue biology and disease - in a way that other, non-human, models such ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...

MDI Bio Lab scientists discovered how zebrafish solve a basic challenge in regenerative biology—insights in their newest publication in the journal Development could one day guide human repair.

Our cells are continually being exposed to environmental assaults. For instance, skin is exposed to pollutants and UV radiation. Our lungs are subject to environmental stimuli such as smoke ...

Every day, your body replaces billions of cells-and yet, your tissues stay perfectly organized. How is that possible? A team of researchers at ChristianaCare's Helen F. Graham Cancer Center & Research ...