Recently, biology professor Anding Shen landed a $300, 000 grant from the National Institutes of Health (NIH) to study the role of endothelial cells in HIV infection—a project that will occupy her for ...

A study published on Sept. 17 in PLOS Pathogens reports results from a clinical trial of an histone deacetylases (HDAC) inhibitor that had shown potential in preclinical studies and answers open ...

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and ...

However, activating NF-kB also has the affect of loosening chromatin, which HIV recruits in another mechanism of latency. Therefore, upregulating the viral activator would be "good for both of these ...

Study dissects HIV reservoir clones that persist on ART, revealing how CD8+ T cells and resistance pathways could be harnessed for future cure strategies.

A major bottleneck in curing HIV (human immunodeficiency virus) is that the virus can hide in an inactive form within resting white blood cells, which play a crucial role in coordinating the immune ...

More than 20 years after the discovery of combination antiretroviral therapy (ART), complete eradication of HIV infection has not yet been achieved. While ART controls viral replication, it is not a ...

HIV is infamous for its ability to hide in the human body for decades, typically requiring long-term treatment to prevent a rebound from dormancy. In a new study, researchers shed light on where and ...

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, ...

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, ...