Abasic sites in DNA are generated by hydrolysis of the N-glycosidic bond that connects the base to the deoxyribose sugar. This occurs either spontaneously, particularly in the case of purines 1, or ...

A piece of research work conducted by the Spectroscopy Group of the UPV/EHU's Department of Physical Chemistry, and the Biofisika Institute provides the cover of the latest issue of the ACS Central ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

As imaging tools continue to get more sophisticated, researchers have been able to actually watch biological processes as they are happening in live cells. Scientists have now visualized loops of DNA ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

Intercalating complexes of rhodium(III) are strong photo-oxidants that promote DNA strand cleavage or electron transfer through the double helix. The 1.2 Å resolution crystal structure of a ...

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism. What’s not captured by this analogy is the fact that our DNA ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed. The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a ...