In a recent review published in the journal Immunity, a group of authors reviewed the role of dendritic cells (DCs) in mediating T-cell responses in cancer, focusing on their interactions at both ...
The data were presented during the Congress of Neurological Surgeons Meeting, September 28 – October 2, 2024, in Houston, TX. Early analysis of the results shows no dose-limiting toxicities or ...
Dendritic cells alter the chemokine gradient they follow to direct themselves to the lymph nodes. An immune response is an impressive feat of collective migration involving many cell types and ...
BETHESDA, Md., June 11, 2025 /PRNewswire/ -- Northwest Biotherapeutics (OTCQB:NWBO) (the "Company" or "NW Bio"), a biotechnology company developing DCVax® personalized immune therapies for solid tumor ...
EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a ...
The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...
Cancer immunotherapy is a strategy that turns the patient’s own immune cells into a “search-and-destroy” force that attacks the tumor’s cells. The “search” immune cells are the dendritic cells, which ...
Treating the brain cancer glioblastoma (GBM) demands more than conventional strategies due to a mix of factors including the cancer’s genetic complexity, invasive growth, and immune resistance. A new ...
Potential autoimmune diseases therapies that target dendritic cells aim to either inhibit immunogenic dendritic cell functions or support their tolerogenic potential (Figure 2). Most strategies ...