Viruses attack nearly every living organism on Earth. To do so, they rely on highly specialized proteins that recognize and bind to receptors on the surface of target cells, a molecular arms race that ...

BIRMINGHAM, Ala. – Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages — the white blood cells that defend the body by killing microbes, ...

Research on preventing type 1 diabetes often focuses on limiting the autoimmune response that destroys the body's ability to ...

Triggering receptors expressed on myeloid cells (TREMs) are a cell surface receptor family found on granulocytes, monocytes, macrophages, and dendritic cells—as well as other myeloid cells in general.

Researchers at UChicago have developed a nanoparticle system that can effectively deliver mRNA to insulin-producing cells, protecting them from the body’s autoimmune response ...

Researchers hope to undertake clinical studies in multiple cancers, including ovarian cancer, glioblastoma, and others.

Though CAR T cells have been effective against certain blood cancers, they have not been for solid tumors. Now, a new form of highly sensitive CAR T cells aims to overcome one of the biggest barriers ...

Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...