To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor ...

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying a specific gene improves the ability of immune cells to combat cancer for ...

A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells ...

RNA modification is a key regulator of neuroblastoma oncogenesis and differentiation. NSUN6, a 5-methylcytosine-specific messenger ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain fatty ...

Waterpipe smoking as deregulator of RNA m6A modification and promotor of epithelial-mesenchymal transition to cause oral cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying a specific gene improves the ability of immune cells to combat cancer for ...

A caffeine-triggered switch that turns CRISPR gene editing on and off inside cells could one day improve cancer therapy.

Knockdown of CUL5 gene enhances CAR-T cells’ prolification and survival compared to conventional CAR-T cells, making them better at fighting cancer. Researchers have identified a method to enhance the ...