The most frequent DNA lesions (8-oxoguanine, thymine glycol, dihydrothymine, dU) (De Bont and van Larebeke, 2014) are removed from the genome by the BER (Kim and Wilson, 2012) (Figure 1). This repair ...
Effects of TKI on patients with non-small cell lung cancer of different stages: A meta-analysis. This is an ASCO Meeting Abstract from the 2018 ASCO Annual Meeting I. This abstract does not include a ...
Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma: CALGB 500104 No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2006 ASCO ...
The genome sustains so much wear and tear, much of it hardly noticeable, that even the small portion of DNA damage that stays unrepaired far exceeds our inventory-taking abilities. Taking stock of DNA ...
DNA repair pathways exist to correct molecular damage caused by internal and external factors. However, any damage to these pathways can result in the creation of tumors and specific types of cancers.
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